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Heres the tricky part: losing weight might mean losing more than just fat

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The rapid transit of carbohydrates into the small intestine results in a fluid shift and a sympathetic response characterized by tachycardia, nausea, and diarrhea

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Its not clear that fasting levels of GLP-1 tell us anything useful because the intestine releases GLP-1 following a meal, and its that post-meal surgenot levels when you havent eatenthats beneficial for blunting appetite and helping the body clear blood sugar