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GLP-1 medications are considered safe when used under medical supervision
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However, whether pharmacological inhibition of the enzyme could elevate oxyntomodulin levels sufficiently to contribute to the therapeutic effect of DPP-4 inhibitor therapy is not known

Given the date range utilized to achieve numbers and duration of follow-up, there was very little use of semaglutide which did not become available in the US market until its approval in December 2017 21

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If someone is experiencing side effects, it is important to have them reach out to a health care provider
