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In conjunction with this edition of Ground Truths theres a podcast with Daniel Drucker , the physician-scientist credited as one of the co-discovers of glucagon-like peptide (GLP-1) nearly 3 decades ago.(Sorry that youre getting 2 emails from me today!) He helps explain some of the new findings that Ill be going through here

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The guide on why you are not losing weight on tirzepatide addresses plateau-breaking strategies that do not require exceeding the maximum approved dose

CMAJ Canadian Medical Association Journal 2023

Oral Semaglutide : Timing : Take the tablet once daily, at least 30 minutes before your first meal, drink, or other oral medications

[2] [4] It's worth noting that naturally produced GLP-1 is rapidly broken down by an enzyme called DPP-4, giving it a very short half-life in circulation