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Neuropeptides (2022) 94:102250
[15] [16] This occurs due to delayed gastric emptying, which can create sensations of fullness, bloating, and queasiness
It's not trying to address hot flashes, joint comfort, inflammation, or the broader range of symptoms that often come with midlife

Ongoing research continues to refine our understanding of this potential complication, and clinicians should remain vigilant for emerging safety data while balancing the substantial metabolic benefits these medications provide for appropriate patients

dose escalation may be delayed if necessary based on tolerability

First-line management includes drinking 1.52 litres of fluids daily, using paracetamol (maximum 4 g daily) or ibuprofen (maximum 1.2 g daily for over-the-counter use) as appropriate, and resting in a quiet environment
