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Glimepiride in Type 2 Diabetes) with linagliptin comparing linagliptin treatment as add on to metformin directly with a therapy with the sulfonylurea glimepiride will bring results later in 2019 and may give additional insights into the association and mechanisms linking hypoglycaemic- with cardiovascular events (69)

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Moreover, as one of the first agents simultaneously approved for type 2 diabetes and weight management, the patient population of tirzepatide is inherently heterogeneous

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