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This pricing model ensures that patients can affordably access treatment regardless of their starting weight or expected dose progression

Specific concerns include post-cholecystectomy syndrome (a cluster of persistent GI symptoms in 1015% of patients) and potential interactions between GLP-1-induced motility changes and pre-existing bile acid malabsorption

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As a side effect, it stimulates appetite signaling in the brain and increases insulin resistance, raising fasting and postprandial blood glucose levels

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Unlike the rarer microvesicular steatosis, which can be very dangerous, macrovesicular steatosis is typically associated with a good long-term prognosis unless it progresses to more advanced liver damage