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, Cook, D

Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration
Loose skin around the abdomen, arms, or thighs can be frustrating, and no amount of continued medication or exercise will resolve it

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Middleton TL, Wong J, Molyneaux L, Brooks BA, Yue DK, Twigg SM, Wu T

This is even applicable to drug development still in the preclinical stage
