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Case reports indicate that metreleptin can markedly improve hepatic steatosis and ALT levels in pediatric patients with congenital leptin deficiency and can be considered in the rare clinical scenario of pediatric obesity and hepatic steatosis due to leptin deficiency [167,168]

2022;102(5S):S1S127

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Taking two doses at once to make up for a missed injection increases the risk of nausea, vomiting, and other serious side effects

doi: 10.1042/bj0010028

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