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This prolonged contact could amplify the medication's irritative effects on the protective mucosa lining your digestive tract

Staying hydrated is also crucial, especially if semaglutide is causing gastrointestinal side effects that might lead to fluid loss

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Patients should seek immediate medical attention for severe, persistent abdominal pain (which could indicate pancreatitis), symptoms of gallbladder disease (right upper quadrant pain, fever, jaundice), or inability to keep any fluids down for 24 hours

Metamucil should be taken at least 2 hours before or after other oral medications, and you should drink at least 8 ounces of fluid with it plus another glass of water afterward