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[46] Preclinical studies suggest semaglutide counteracts these processes by activating the AMPK and SIRT1 pathways, which are fundamental for cellular autophagy and mitophagy

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10.1161/CIRCULATIONAHA.111.037283 [DOI] [PubMed] [Google Scholar] Leon B

Abstract Molecular communications in the gutbrain axis, between the central nervous system and the gastrointestinal tract, are critical for maintaining healthy brain function, particularly in aging

doi: 10.1007/s11064-017-2384-8

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