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51 , 53 , 54 Mediation analyses estimated that approximately 68% of the SBP reduction and 71% of DBP reduction were attributable to weight loss, 53 suggesting that nearly one-third of the effect arose from alternate pathways

Seven additional Phase 3 trials are expected to complete in 2026

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One honest caveat from the data: because the Phase 2 curve had not clearly plateaued by the end of the study, the full ceiling of the effect is genuinely not yet known that is one of the questions the Phase 3 TRIUMPH program is designed to answer

received funding from Socit Francophone du Diabte (SFD)

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