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Obesity affects 42% of adults in the United States and is strongly associated with major cardiovascular disease risk factors, including high blood pressure, abnormal cholesterol levels, and insulin resistance, making effective obesity treatment a critical public health priority.

This article examines the clinical evidence, delivery mechanism challenges, and how genetic predispositions in GLP-1 pathways may inform discussions with healthcare providers about ava

In a newly published study with Elisabetta Patorno and colleagues, we examined severe motility-related GI events, including gastroparesis, gastrointestinal obstruction, and severe constipation requiring hospitalization, among adults with type 2 diabetes initiating GLP-1 RAs vs SGLT-2 inhibitors

Manage it by eating smaller portions slowly, choosing bland foods, keeping well-hydrated with water, and avoiding heavy, greasy meals

monitoring protocol, symptom timeline, safe restart criteria.

Semaglutide injections have transformed weight loss treatment for millions of people by reducing hunger and increasing feelings of fullness