glp-1 drugs history Timeline of discovery and clinical development. (a) Key events in The expanding landscape of GLP-1

In the two-year STEP 5 study, 77.1% of participants lost at least 5% of their body weight , and 36.1% achieved a reduction of 20% or more

Committing up front offers lower rates, which is appealing if you plan to stay long term

[DOI] [PubMed] [Google Scholar] 252.Christensen L.W., Kuhre R.E., Janus C., Svendsen B., Holst J.J

This post hoc analysis aimed to assess the effects of SGLT2i-GLP-1RA combination therapy on BP control in patients with type 2 diabetes (T2D)

That's like to be determined

Moreover, we retrieved other relevant records 56,57,58 : two large ( N = 133,318 and N = 342,608, respectively) cohort studies in people with diabetes across 613 years noted a beneficial association between GLP-1RA prescriptions compared with non-prescription and lower diagnoses of dementia 57,58 , while a small ( N = 154 patients with T2DM) and shorter (~12 months) cross-sectional investigation of GLP-1RAs in addition to metformin, compared with metformin alone, observed better MoCA scores in the former group 56