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Overall treatment discontinuation rates due to adverse events were 6% (3 mg), 4% (12 mg) and 8% (36 mg) for orforglipron vs
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The researchers acknowledged study limitations, including possible outcome misclassification because of the use of diagnostic codes not validated in claims data, potential underrecording of GI adverse events in the claims databases, and not being able to rule out possible residual confounders from certain factors like BMI
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Signs of deficiency may include: Megaloblastic anemiaa condition of larger than normal red blood cells and a smaller than normal amount
