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The GIP-induced peripheral promotion of positive energy balance is likely to be far less effective than the GLP- 1/GIP dual agonist's direct action on the central nervous system, which results in satiety and weight loss

Meanwhile, the benefits of these medications are undeniable

You can reach out to your medical provider and adjust your treatment plan anytime

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For now, tesamorelin and retatrutide remain promising tools for metabolic studies, but their combined use requires further investigation to establish protocols and assess long-term outcomes

Any therapy is tailored to your biology and monitored by a provider