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Of course, some patients dont mind injections and may prefer a weekly dose for convenience, while others may favor a daily pill, especially if they already take other daily medications

Pfeifer KJ, Selzer A, Whinney CM, Rogers B, Naik AS, Regan D, et al

31 In addition, studies examining the electrophysiological properties of hypothalamic neurons upon GLP-1 receptor activation also applied 100 nM Ex-4 32 or the effective submaximal dose of 1 M Ex-4, a concentration that is 10-fold greater than we used in our experiments

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Pasireotide frequently causes severe hyperglycemia, probably by activating somatostatin receptor 5 expressed in the pancreases and intestines 17,18

Due to the direct and indirect role of GLP-1 on endothelial functions, GLP-1 receptor antagonists may also serve as potential prospects in addressing cardiovascular risks in T2DM patients [119]