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In the meta-analysis, HRs from the individual trials were pooled according to metformin use at baseline using the fixed- and random-effect method
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doi: 10.1016/S0306-4522(96)00434-4 [DOI] [PubMed] [Google Scholar] 29.Kappe C, Tracy LM, Patrone C, Iverfeldt K, Sjholm
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Numerous patients have reported gastrointestinal issues after taking the drug, including gastroparesis or stomach paralysis
