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Description
O GLP-1 pode agir de forma direta, se ligando em receptores nos neurnios no ncleo arqueado no hipotlamo (e inibir a fome) e tambm de forma indireta, estimulando a secreo de insulina, a qual tambm estimula os neurnios do ncleo arqueado

Pfeffer MA, Claggett B, Diaz R, Dickstein K, Gerstein HC, Kober LV, Lawson FC, Ping L, Wei X, Lewis EF, Maggioni AP, McMurray JJ, Probstfield JL, Riddle MC, Solomon SD, Tardif JC

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