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Description
Mean (SD) [ 68 Ga]Ga-DO3A-Exendin-4 binding in pancreas uptake was decreased from SUV 55min 2.98 (0.74) at baseline to SUV 55min 1.46 (0.37) at a dose of 0.2 mg SAR425899 (Fig
WC : Waist circumference
Advanced Metabolic Signaling Research
A 48-week phase 2 study using a MAD strategy demonstrates a decrease in mean body weight of 8.7% with 1 mg, 17.1% with 4 mg, 22.8% with 8 mg, and 24.2% with 12 mg, compared to 2.1% with placebo (105)
doi:10.3109/09513590.2014.975686 Szczesnowicz A, Szeliga A, Niwczyk O, Bala G, Meczekalski B
A more detailed discussion of safety and tolerability are provided later
