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As proof of concept, bariatric surgery has been associated with a decreased prevalence of obesity-related cancers, including PDAC, illustrating the key role of weight management for cancer prevention 3,4

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Altered Food Preferences: When tired, individuals often crave high-calorie, high-carbohydrate foods

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Preliminary safety reporting indicated: GI adverse event profile consistent with Phase 2 data No new safety signals identified beyond those observed in earlier trials Discontinuation rates due to adverse events were comparable to other GLP-1 class trials Full adverse event tables from TRIUMPH-4 are expected with the peer-reviewed publication

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Patient Profiles They found that patient age, baseline BMI, and co-morbidities influenced results with retatrutide

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