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Biosimilar development initiatives by companies including Samsung Bioepis, Sandoz, and generic manufacturers will introduce competitive pricing pressure beginning approximately 2031 to 2032 when Novo Nordisk's patent protections expire for core Semaglutide formulations

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Our analysis of around 100 000 patients provides a robust basis for reassessing an indication expansion and new indication approval in heart failure. The study focused on heart failure with preserved ejection fraction or HFpEF, in which the hearts ability to pump remains intact but the stiffened heart muscle does not fill properly with blood

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