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The weight loss platform Noom recently launched its compounded GLP-1 microdose injections that claim to promote weight loss with fewer side effects.

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The evidence suggests not.

It is taken once a week through a subcutaneous injection (under the skin) using a pre-filled injector pen

A comprehensive literature search was conducted across the PubMed, Embase, and Google Scholar databases for peer-reviewed articles published from inception through June 15, 2026, focusing on the landmark SURPASS, SURMOUNT, and SUMMIT trial programs, relevant cardiorenal post hoc analyses, emerging body recomposition trials, and real-world cohort-switching protocols

Type 2 diabetes mellitus (T2DM) often requires pharmacological management, with newer agents like glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RA) and dual gastric inhibitory polypeptide (GIP)/GLP-1 receptor agonists offering metabolic and cardiovascular benefits