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2024 Feb 19;69:102475

Multiple mechanisms have been proposed to explain these observations, though the precise pathways remain an active area of research
Guedes, E

Cardiovascular considerations : Wegovy typically increases heart rate by approximately 2-4 beats per minute, and cannabis useparticularly smokingcan also elevate heart rate and blood pressure acutely

That translates to roughly 50 pounds for someone who weighs 240 pounds

doi: 10.1016/j.jviscsurg.2024.12.003
