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GLP-1 Medications for Weight Loss Several GLP-1 drugs have specific FDA approval for weight loss

The standard AOD-9604 dosage protocol runs 300 to 500 micrograms per day administered subcutaneously, typically on an empty stomach in the morning to maximize fat oxidation during fasting periods

liraglutide-treated patients exhibited greater weight loss79), although patients receiving once-weekly exenatide maintained this weight loss for a longer duration1)

There isn't a lot of research on the health effects of periodic use, though other studies show weight regain after stopping GLP-1s is faster compared to other diets that focus on behavior changes

If dietary measures are insufficient, over-the-counter fiber supplements (psyllium, methylcellulose) or osmotic laxatives (polyethylene glycol) may be appropriate after discussing with your healthcare provider