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Obesity Facts, 9(6), 365378
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Phase 3 Update: TRIUMPH-4 Results Preliminary data from the ongoing Phase 3 TRIUMPH-4 trial (68 weeks) shows higher numbers than Phase 2: 12mg dose: 28.7% average weight loss (~71 lbs / 32 kg) 9mg dose: 26.4% average weight loss (~64 lbs / 29 kg) Knee osteoarthritis pain: 76% reduction (significant quality-of-life improvement) Blood pressure: Average reduction of 14 mmHg Full Phase 3 results across the TRIUMPH program (obesity, diabetes, cardiovascular outcomes, kidney outcomes) are expected throughout 2026
[DOI] [PubMed] [Google Scholar] 61.Mullins R.J., Mustapic M., Chia C.W., Carlson O., Gulyani S., Tran J., Li Y., Mattson M.P., Resnick S., Egan J.M., et al
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