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Table 1: Adverse Reactions in Two Pooled Clinical Trials of 26 Weeks and 16 Weeks Duration in Adults with Type 1 Diabetes (with incidence 5%) Table 2: Adverse Reactions in Three Pooled Clinical Trials of 26 Weeks Duration in Adults with Type 2 Diabetes (with incidence 5%) Hypoglycemia Hypoglycemia is the most commonly observed adverse reaction in patients using insulin, including TOUJEO [see WARNINGS AND PRECAUTIONS ]

Furthermore, the mTOR signaling pathway also plays a role in neurogenesis, dendritogenesis, and LTP (Jaworski and Sheng, 2006)

Nevertheless, insulin sensitivity is also rapidly improved after bariatric surgery, and some studies suggest that GLP-1(9-36) and its degradation products, which circulate at elevated levels after bariatric surgery, may enhance insulin sensitivity in peripheral tissues

doi: 10.1111/obr.13435 8 Financial results of Novo Nordisk

Mountjoy M, Sundgot-Borgen J, Burke L, et al

Contact your healthcare provider if symptoms worsen or you develop nausea or vomiting