glp 1 drugs and birth control GLP-1 agonist tirzepatide oral contraceptives GPs could bulk-warn patients about

Missing injections disrupts the steady-state concentration that the medication needs to work effectively

GLP-1RAs, which achieved great success in 2023 and draws peoples attention back to obesity treatments and GLP-1 therapies worldwide, was chosen as the breakthrough of year 2023 by Science [2]

this article focuses on GLP-1 receptor agonists for glycaemic control in type 2 diabetes

Phase 2 trial results (48 weeks, adults with obesity): 1 mg dose: 7.2% body weight loss 4 mg dose: 12.9% body weight loss 8 mg dose: 17.3% body weight loss 12 mg dose: 24.2% body weight loss Placebo: 1.6% body weight loss Phase 3 TRIUMPH-4 results: 9 mg dose: 20.0% body weight loss (22.9 kg / 50.5 lbs) 12 mg dose: 23.7% body weight loss (27.2 kg / 60.0 lbs) Placebo: 4.6% body weight loss In a separate phase 3 analysis, retatrutide at the highest dose achieved up to 28.7% weight loss

Obesity is the biggest risk factor for Type 2 diabetes, and substantial weight loss can help in reversal and remission of the disease, as well as reduced risk for conditions like high blood pressure, dyslipidemia, heart disease, and stroke

But as with any new medication option, understanding the differences between the pill and injectable forms is essential for making informed decisions about your care