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For context, 10-15% of the general population tests positive for SIBO or IMO

Formulation and administration: Ozempic and Wegovy are both subcutaneous injections administered once weekly, but they use different delivery devices

This biological hunger can hit all at once, leading to a restart of the binge cycle even when on medication , or can come back with a vengeance when finishing weight loss medication , if binge eating patterns have not been addressed separately

For women who already had GERD before starting GLP-1 therapy, the medication commonly worsens the existing condition in the early months

Arterioscler Thromb Vasc Biol 33:393399

More concerning from a clinical perspective is the potential for lean mass loss associated with rapid weight reduction