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PMID: 18277116 Article Published Date : Feb 01, 2008 Study Type : Human Study [+] Vitamin E supplementation may reduce oxidative DNA damage and autoantibody production in systemic lupus eryhematosus

The most commonly reported adverse effects in Phase 2 trials were gastrointestinal in nature, including: Nausea (the most frequently reported) Vomiting Diarrhoea Constipation Decreased appetite These effects were generally dose-dependent and most pronounced during dose escalation, typically improving over time

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In trials, tirzepatide (Zepbound for weight loss and Mounjaro for diabetes treatment) also reduced A1C better than semaglutide (Wegovy and Ozempic)

This includes adults with an initial BMI of 30 kg/m 2 and above, or 27 to 29.9 kg/m 2 with at least one weight-associated comorbidity (e.g hypertension, dyslipidaemia, obstructive sleep apnoea, cardiovascular disease, prediabetes or T2DM)