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GLP-1 reduces neuroinflammation and also affects centers in the brain that are responsible for impulse control and reward signaling there are many studies showing that we indeed have GLP-1 receptors in our brain

[DOI] [PMC free article] [PubMed] [Google Scholar] 127.Brandt, S

Being overweight made it hard for me to move, and the constant hunger at night kept me up all night
Consider adding either GLP-1 RA or tirzepatide, either as part of initial therapy or as first add-on, to achieve individualised glycaemic target

Also, take a multivitamin at least 2 hours before or after taking orlistat because the drug temporarily makes it harder for your body to absorb vitamins A, D, E, and K

Pediatric patients need to have a BMI in the 95th percentile for their age and gender
