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Description
The cormorbidities often associated with HFpEF such as obesity, diabetes mellitus, and hypertension as well as the metabolic changes associated with them are known to induce a state of inflammation that affects cardiac metabolism, as well as coronary vascular injury and ischemia [5]
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In a Phase II trial for NASH, 59% of semaglutide-treated participants achieved NASH resolution compared to 17% on placebo, with no worsening of fibrosis
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Angiotensin AT1/AT2 Receptors: Regulation, Signalling and Function
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