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In New Zealand, GLP-1 products approved for use for weight management are types of liraglutide (Saxenda, Victoza, Benedo) and semaglutide (Ozempic, Wegovy), the Ministry of Health said

The PK profile depends on molecular structure, administration route, and pharmacological properties

This could point to the defendants understanding that their GLP-1 drugs can indeed lead to vision loss in some patients

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In this experiment, the high protein diet can promote intestinal secretion of GLP-1, improve FGF21 resistance, upregulate LKB1 to activate the AMPK pathway, downregulate the expression of SERBP-1c mRNA and protein in the liver, and ultimately inhibit liver lipid synthesis [50]

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