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Supplementary Materials Data Availability Statement Data will be made available on request.

The development reflects a significant shift in the pharmaceutical landscape as Canada becomes one of the first countries where regulatory exclusivity related to this medication has expired

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How I Approach This With Patients Currently on GLP-1 Medication For patients actively using GLP-1 medications who come to me proactively, before significant skin changes have developed, I focus the conversation on prevention and monitoring rather than correction: supporting skin's structural health through appropriate topical actives, discussing realistic expectations about the pace of weight loss and its relationship to skin's ability to adapt, and establishing a baseline so we can track changes over time rather than only reacting once laxity has become significant

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