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But the human risk appears vastly lower than rodent models suggested
Accessed May 31, 2026.
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These include the potential for diabetic retinopathy progression and the rare but serious risk of non-arteritic anterior ischemic optic neuropathy (NAION)
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While the FDA couldnt rule out a small risk, it noted that a study funded by the NIH found patients on semaglutide had a lower risk of suicidal thoughts compared to those on other diabetes and anti-obesity medications
In 1993, Nauck et al
