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However, exposure to heat or extended time outside the fridge can reduce effectiveness

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Medication may help reduce the constant urge to snack, making or eating smaller portions, and support better control around meals

Weight reduction is likely a major contributor, through reduced biomechanical stress, but other pathways can't be excluded

For patients with pre-existing diabetic retinopathy, ophthalmologic follow-up is recommended, particularly during periods of rapid glycemic improvement

Specifically, after 30 weeks, 36.7% of patients receiving exenatide twice-daily were antibody-positive