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Understanding how GLP-1 regulates inflammation (Figure 1) provides insights into the pleiotropic weight lossindependent benefits of GLP-1R agonism, potentially explaining its actions to reduce the severity of several chronic diseases marked by dysregulated immune function and inflammation

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Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure
In pursuit of more effective obesity treatments, researchers are studying the combined use of GLP-1 with other incretin hormones (such as GIP , glucagon , and amylin ) to enhance weight reduction and cardiovascular metabolic improvements

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