glp-1 long term risks Long-Term Effects Of GLP-1s: & Benefits – Forbes Health The GLP-1 Trap: Your Jumpstart
Description
One real-world evidence study found that patients receiving GLP-1 receptor agonists had a higher risk of ulcerative colitis compared to those on DPP-4 inhibitors (a different diabetes drug class)

N., Gour, A., Sharma, A., Urs, N., Warren, B., & de Lartigue, G

After the initial rapid drop in weight, you may notice the rate of weight loss starting to slow down, especially between 12 and 36 weeks

McGowan is concerned about using compounded GLP-1 drugs, which dont get the same level of FDA oversight

However, using a novel Nb37-based BRET approach to monitor activation of endogenous G proteins close to GLP-1R, we demonstrate here that exendin-4-C16 shows increases in G s activation in spite of its lower mini-G s recruitment efficacy
Marathe CS, Rayner CK, Bound M, et al
