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I worry that in dealing with people with cravings, and people at risk of overdosing and other problems, that we need to understand and appreciate the uncertainties here more. He says that another issue that must be explored further before prescribing GLP-1s to prevent or treat addictions is the ability of the brain to adapt

Slow titration doesn't just feel betterit actually leads to better adherence and outcomes

For others, particularly those with a longer history of complicated relationships with food, dieting, or their bodies, those concerns can grow into something that occupies more mental space than feels comfortable

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