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doi: 10.1111/obr.70079

PMID: Summary Keywords Crohns disease, GLP, GLP-1, GLP-2 receptor agonist, IBD - inflammatory bowel disease, ulcerative colitis Citation Lee JJ, Bajgain P and Lightner AL (2026) GLP-1 and GLP-2 as intestinal reparative therapies in inflammatory bowel disease: mechanisms, translation, and clinical opportunity

They enhance glucose-dependent insulin secretion, suppress glucagon release, delay gastric emptying, and reduce appetite, thereby contributing to glucose homeostasis and body weight regulation ( 4.2 Tirzepatide in weight regulation and metabolic improvement Obesity is one of the major risk factors for OSAS, and weight reduction has been associated with improvements in OSAS-related symptoms
Over time, AGEs undergo further irreversible modifications that disrupt cellular and tissue function

95% CI, 0.72-1.37) and as a competing event (HR, 1.01

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