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Ozempic was FDA-approved in 2017 for blood sugar control in adults with type 2 diabetes

Metabolic Improvements Blood sugar: Average HbA1c reductions of 0.5-1.0 percentage points in non-diabetic patients, 1.6+ points in diabetic patients

tirzepatida activa GLP-1 y GIP (agonista dual)

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Nowadays, it has developed various classes of peptide-based multi-agonists, and peptide-small molecule conjugates with probed superior preclinical efficacy and is currently undergoing clinical evaluation (Clemmensen et al., 2019)

Its associated with long-term complications including hypertension, stroke, heart failure, and impaired quality of life