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Injection instructions for GLP-1 medications in the thigh: When injecting in the thigh, select the front or outer area of your thigh
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In the general population, these are usually transient and mild

Exenatide improves excessive daytime sleepiness and wakefulness in obese patients with type 2 diabetes without obstructive sleep apnoea
Clinical trials have demonstrated that tirzepatide produces dose-dependent reductions in hemoglobin A1c (HbA1c) of up to 2.5% in type 2 diabetes

On the other hand, the risks of HHF (HR 0.93, 95% CI 0.831.04 with GLP-1RAs and HR 0.69, 95% CI 0.610.79 with SGLT2is) and composite kidney outcomes excluding macroalbuminuria (HR 0.92, 95% CI 0.801.06 with GLP-1RAs and HR 0.55, 95% CI 0.480.64 with SGLT2is) significantly reduced with SGLT2is only
