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They lower blood glucose by helping the kidneys remove excess glucose through the urine

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The top lipid metabolite 8-HETE (8-Hydroxyeicosatetraenoic Acid), an oxidized lipid mediator, modulates GLP1R sensitivity and signaling, influencing metabolic responses and insulin secretion dynamics 82

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pre-clinical studies suggest that GLP-1 receptor activation may modulate inflammatory and immune responses that affect the brain [137]
