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Technical Guidance for Clinical Trials of Drugs for the Treatment of Adults with Type 2 Diabetes (China National Medical Products Administration, 2023)

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Alcohol is a diuretic, promoting fluid loss through increased urination

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Dysentery Diarrhea Angiodysplasia Ischemic colitis Out of the above causes, hemorrhoids, anal fissures, constipation, diarrhea, and hard stools are commonly seen in daily practice

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CALIFORNIA WARNING

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Always swirl gently instead

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doi: 10.1136/bmjopen-2016-013927 77 ElSayedNAAleppoGArodaVRBannuruRRBrownFMBruemmerDet al

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