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Physiologically and pharmacologically, the CeA plays a role in mediating the leptin function to suppress appetite and food intake

As a convenient once daily pill with no dietary restrictions, orforglipron represents the latest incretin medicine and a significant advancement in incretin-based treatments

Also known as semaglutide, Ozempic is a once-weekly injection for those with type 2 diabetes

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By activating GIP and GLP-1 receptors, tirzepatide enhances insulin secretion when blood glucose levels are elevated, suppresses glucagon release, slows gastric emptying, and reduces appetite through effects on brain centers that control hunger