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Obesity is a prevalent, complex, progressive, and relapsing disease characterized by excessive or abnormal body fat, which negatively impacts health

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Resistance training is one of the most effective stall-breaking interventions available

Drug-Free MN for Obesity Treatment Gelatin, as a natural polymer, has wide applications in drug delivery systems due to its good biocompatibility and biodegradability [42]

Nuclei isolation from the anatomical preparation was quality controlled by FACS sorting (see Supplementary material online, Figure S8 ) prior to measurements