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It is possible, but the quality of weight loss is significantly worse without resistance training, especially for HRT users whose muscle mass is already vulnerable

Earlier this month (June 2025), Novo Nordisk reported that it will advance to Phase III trials both subcutaneous and oral amycretin in weight management based on completed clinical studies

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In addition, the known delayed gastric emptying may impair the absorption of oral medications, including oral contraceptive pills, thus underscoring the importance of counselling patients and educating prescribers for concerted multiprofessional management [138]

doi: 10.1161/CIRCULATIONAHA.112.091215 39 GuoZQiWYuYDuSWuJLiuJ

What to know Obesity is a known risk factor for breast cancer, so could some women reduce their odds of this common type of cancer by taking weight-loss drugs such as Wegovy and Zepbound