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Although GLP-1 class medications have been on the market for 2 decades now, rarer serious side effects are now being seen more simply due to recent increases in the number of people on these medications3

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The researchers suggest hormone therapy may enhance GLP-1 effects through estrogen's known actions on glucose metabolism, lipid processing, and visceral fat distribution

Vella, Mechanism of Action of DPP-4 InhibitorsNew Insights, J

Future experiments will determine whether loss of Klb expression in these neuronal populations impairs GLP-1RA weight loss across multiple high carbohydrate diets

( Epub 2019/01/15 )