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This upgrades the therapeutic goal from weight loss to comprehensive reproductive health management. 6.5 Preconception pathway: smooth transition from metabolic optimization to conception The goal of periconception management is not merely to achieve the lowest possible weight, but to ensure the patient enters a window of relative weight and metabolic stability after an adequate washout before attempting conception

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In a two-year study, Wegovy users lost an average of 35 pounds, compared to 6 pounds in the placebo group (Managing Weight WIth Wegovy, n.d.)

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GLP-1R agonist 13 GLP-1R agonist 13 (Compound 24) is a GLP-1 receptor agonist

Additionally, we obtained a time-resolved cell membrane interactome map for the receptor in cells