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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Chlebowski R.T., Aragaki A.K., Anderson G.L., Pan K., Neuhouser M.L., Manson J.E., Thomson C.A., Mossavar-Rahmani Y., Lane D.S., Johnson K.C., et al

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Many patients find that symptoms improve over time as their digestive system adapts to the medication's effects on gastric motility, though the timeline for improvement varies among individuals

One hypothesis is that this phenomenon is caused by the elevated postprandial GLP-1 and consequently insulin levels after RYGB

When you take semaglutide, it mimics the natural GLP-1 hormone that your intestines produce after eating

Author Contributions Concept and design: John Bacon, Sommer Sekhon, Ibaadat Sukhmanii Kahlon Acquisition, analysis, or interpretation of data: John Bacon, Sommer Sekhon, Ibaadat Sukhmanii Kahlon Drafting of the manuscript: John Bacon, Sommer Sekhon, Ibaadat Sukhmanii Kahlon Supervision: John Bacon Critical review of the manuscript for important intellectual content: Ibaadat Sukhmanii Kahlon References 1.Ischaemic colitis: practical challenges and evidence-based recommendations for management