tirzepatide for type 2 diabetes FDA approves new version of drug Mounjaro to be sold weight loss VisualAbstract: Once-weekly tirzepatide significantly improves

Semaglutide influences gut hormone signaling and metabolic function, but claims of gut healing require careful interpretation

Here is what the data show, from GI effects to the thyroid boxed warning.

The observations that GLP-1 receptor agonists exert anti-inflammatory actions in preclinical studies, taken together with case reports linking improvements in psoriasis with GLP-1 receptor agonist therapy, illustrates the emerging clinical implications of non-classical anti-inflammatory actions of incretin-based therapeutics.

Diabetes Obes Metab

However, the molecular details of ago-allosterism remain elusive

Its observational and not proof of causation, but the signal is compelling